Antibody Drug Conjugate Market Growth Factors, Company Profile Analysis, Research Methodology and Forecast to 2027
Market Analysis
The global antibody drug conjugate (ADC) market is projected to witness
a stupendous growth at a notable 19% CAGR over the predicted years. ADCs are
made of three parts- first a specific antibody for binding, an antigen that has
limited expression on the normal cells, second a cytotoxic agent to kill target
cancer cells and third a chemical linker to attach the cytotoxic agent to the
antibody. This is how antibody drug conjugates work. They are the new age of
therapeutic agents. One of the key advantages of antibody drug conjugates is
that this will help in bringing together the finest characteristics of both
antibodies as well as the chemotherapy’s cytotoxic potential.
There are many factors that is fueling the growth of the antibody drug conjugate
market. The different market trends and factors in this market according to an
analysis performed by Market Research Future (MRFR) include increasing prevalence
of cancer, advancement in medical technology, increased investment in R &
D, efficacy of ADC in treating diseases, rising collaboration amid
biotechnology and biopharmaceuticals and research institutes, preclinical
research, growing geriatric population and rise in obese population. On the
contrary, the soaring cost related to the procedure may hamper the growth of
the antibody drug conjugate market.
Market Segmentation
As per MRFR report, the global antibody drug conjugate market is
segmented on the basis of type, product, technology, application and end-user.
Based on type, it is segmented into drug/toxin, linker, monoclonal
antibodies and others. Of these, the antibody drug conjugate linker is expected
to have the maximum share in the antibody drug conjugate market.
Based on application, the antibody drug conjugate market is segmented
into lymphoma, multiple myeloma, solid tumors, skin cancer, breast cancer,
colon cancer, lung cancer, glioblastoma, ovary cancer, pancreas cancer, kidney
cancer, prostate cancer and leukemia. Leukemia is further segmented into
Chronic Lymphocytic Leukemia (CLL), Acute Lymphocytic Leukemia (ALL), Chronic
Myeloid Leukemia (CML), and Acute Myeloid Leukemia (AML). Of these, breast
cancer had the maximum share owing to its increasing prevalence.
Based on product, it is segmented into Kadcyla, Adcertis and others.
Based on technology, the antibody drug conjugate market is segmented
into Immunomedics technology, Seattle Genetics technology, ImmunoGen technology
and others.
Based on end-user, it is segmented into biopharmaceutical companies,
biotechnology companies, academic research institutes, specialized cancer and
others.
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Regional Analysis
Based on region, the antibody drug conjugate market covers growth
opportunities and latest trends across North America, Europe, Asia Pacific and
Middle East and Africa. Of these, North America is expected to accrue maximum
share in the market due to advancement in manufacturing techniques,
technological innovation and contribution of nanotechnology to create ADC. The
U.S. FDA has given approval to only three ADC. The antibody drug conjugate
market in Europe will have the second largest share followed by the APAC
region. APAC is an emerging market and the factors that are driving the growth
of the market include increasing government initiatives. A good number of
products are under the pipeline and such developments are performed under
license agreements.
Key Players
Leading players profiled in the antibody drug conjugate market include
Synthon (U.S.), Mersana Therapeutics (U.S.), Oxford BioTherapeutics (U.S.),
Heidelberg Pharma (Germany), Progenics Pharmaceuticals (U.S.), Astellas
Pharma/Agensys (Japan), Bayer HealthCare (Germany), Agensys, Inc. (U.S.),
Concortis Biotherapeutics (U.S.), Genentech (U.S.), AbbVie Inc. (U.S.),
Millennium Pharmaceuticals (U.S.), Celldex Therapeutics (U.S.), Pfizer Inc.
(U.S.), Immunomedics (U.S.), Antikor (U.K.), Roche Holding AG (Switzerland), ImmunoGen,
Inc. (U.S.), and Seattle Genetics (U.S.).
Feb 2019- The Food and Drug Administration (FDA) has granted priority
review to ADC (antibody drug conjugate) for diffusing large B-Cell Lymphoma.
The chief medical officer of global product development is working with the
Food and Drug Administration for bringing this vital novel option to patients
having this aggressive ailment as fast as possible. The FDA is most likely to
come up with the decision by August 19, 2019.
Jan 2019- Daiichi Sankyo has come up with a late-stage study of ADC to
treat patients having low expressing HER2 metastatic/unresectable breast
cancer.
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